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The current quantity is the 1st of a projected four-volume treatise. This quantity includes the subsequent chapters: "Synthesis and response of Pyrimidine Nucleosides," "Synthesis and homes of Purine Nucleosides and Nucleotides," and "Synthesis and homes of Oligonucleotides." those 3 chapters have been chosen for inclusion in quantity I as the parts have supplied the foundation and impetus for the initiation and improvement of the opposite components of study, with a view to be defined in next volumes. every one bankruptcy is very complete in nature and will supply a prepared reference resource for not just the beginner but additionally the skilled investigator or researcher. The chapters were ready by way of authors with enormous event in each one specific sector of analysis, and this has ended in a lucid presentation of every well-defined region. those volumes have been designed with medicinal chemists, medicinal natural chemists, natural chemists, carbohydrate chemists, actual chemists, and organic chemists in brain. notwithstanding, as a result large fresh curiosity during this learn zone because of the organic and chemotherapeutic review of nucleosides and nucleotides as anticancer, antiviral, and antiparasitic brokers, those volumes must also be worthy additions to the libraries of virologists, biochemical pharmacologists, oncologists, and pharmacologists. we wish to thank the authors for his or her enthusiasm and help make those volumes on hand to the clinical neighborhood.

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